Activation and Optimization of Teamwork Leonardo da Vinci was known to be the last universal genius. He was educated in all scientific fields and combined various talents such as intuition, creativity, analytic thinking as well as the capability to raise interest for his ideas. Nowadays, the knowledge and comlexity within the fields of engineering, production and management have multiplied. Ingenuity has become a matter of many rather than few. Teamwork has become ever more important in the course of the last decades. Leonardo 3.4.5 concentrates on the team as the key to improvement of performance. The programme's ultimate goal is to activate and optimize teamwork within companies. Leonardo 3.4.5 gets away from hierarchical structures and approaches the ideal of team-based organisations. The software tool of Leonardo 3.4.5 analyses and structures teams on the individual level (3), the group level (4) and the organizational level (5). J.G. Miller's theory of living systems serves as a model in this respect. A questionnaire serves as means to develop personal profiles of the employees. The questionnaire is no test, though. It is a means to achieve higher rates of satisfaction among team members. Leonardo 3.4.5: Whom for and for what?